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Image Search Results
Journal: Scientific Reports
Article Title: Modulation of Central Carbon Metabolism by Acetylation of Isocitrate Lyase in Mycobacterium tuberculosis
doi: 10.1038/srep44826
Figure Lengend Snippet: ( A ) Differential growth of Δ npdA using the BIOLOG Phenotype Microarray TM plates. Data are from duplicate plates. The log 2 ratio (Δ npdA /WT) was plotted and the standard deviation was plotted as the dashed lines. ( B–D ) Δ npdA exhibited better growth under acidic pH. KO: Δ npdA ; COM: the complemented strain. Results are combined data (mean ± s.d.) from two independent experiments, and each experiment was done in triplicate.
Article Snippet: Phenotype microarray experiments were carried out using the BIOLOG
Techniques: Microarray, Standard Deviation
Journal: Cell
Article Title: A white-box machine learning approach for revealing antibiotic mechanisms of action
doi: 10.1016/j.cell.2019.04.016
Figure Lengend Snippet: (A) Overall experimental design for measuring metabolite effects on antibiotic lethality. Overnight cultures of E. coli MG1655 were inoculated into MOPS minimal medium, grown to early exponential phase, and back-diluted to OD600 = 0.1. Cells were dispensed into Biolog phenotype microarray plates (PMs) 1–4 (Bochner, 2009) with different concentrations of ampicillin (AMP), ciprofloxacin (CIP) or gentamicin (GENT) added. OD600 was measured after 4 hours of incubation at 37°C and 900 rpm shaking. Antibiotic IC50s were estimated for each antibiotic-metabolite combination.
Article Snippet: Cells were dispensed into
Techniques: Microarray, Incubation
Journal: Cell
Article Title: A white-box machine learning approach for revealing antibiotic mechanisms of action
doi: 10.1016/j.cell.2019.04.016
Figure Lengend Snippet: Key Resources Table
Article Snippet: Cells were dispensed into
Techniques: Virus, Recombinant, Microarray, Software, Combined Bisulfite Restriction Analysis Assay